11-09-2013

Catalan scientists discover that the hormone FGF21 protects the heart

The research group led by Dr. Francesc Villarroya, from the University of Barcelona, has shown, in a study performed in rodents, that the hormone FGF21 has a protective function against cardiac hypertrophy. The study, published last June in Nature Communications, shows that the lack of FGF21 is associated to cardiac dysfunction, while treatment with this hormone reverses these alterations in mice. FGF21is produced in the heart and it is released to protect cardiac cells against hypertrophic insults. These results open new avenues in the investigation on the prevention and treatment of cardiac diseases.